Methyl tetracosanoateMethyl tetracosanoate
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Methyl tetracosanoate

Methyl lignocerate; C24:0 Methyl ester

This high purity fatty acid methyl ester is ideal as a standard and for biological studies. Lignoceric acid (C24:0) and nervonic acid (C24:1) can make up as much as 60% of the fatty acids of certain lipid fractions in the white matter, gray matter, and myelin of the human brain.1 Sphingomyelin also contains significant amounts of both lignoceric and nervonic acids in other mammalian sources.2 Lignoceric acid is oxidized mainly in the peroxisomes in contrast to some of the other fatty acids, such as palmitic acid, which are oxidized in the mitochondria.3 In peroxisomal disorders, such as Zellweger cerebro-hepato-renal syndrome and X-linked adrenoleukodystrophy, there is an accumulation of lignoceric acid along with other saturated very long-chain fatty acids due to peroxisomal dysfunctions. Lignoceric acid (as well as other saturated very long-chain fatty acids) promotes the growth of cotton fiber cell elongation (possibly by activating ethylene biosynthesis) and increases sphingolipid biosynthesis.4
Cat# Size Price Qty Buy
1038 100 mg £84.38

Additional Information

Property Value or Rating
Product Size 100 mg
Manufacturer Matreya, LLC
Empirical Formula C25H50O2
CAS# 2442-49-1
Formula Weight 382
Solvent none
Source synthetic
Purity 99%
Analytical Methods GC
Solubility chloroform, ethyl ether
Physical Appearance solid
Storage room temperature
Dry Ice No
Hazardous No
References

1. J. O’Brien and E. Sampson “Fatty acid and fatty aldehyde composition of the major brain lipids in normal human gray matter, white matter, and myelin” Journal of Lipid Research, vol. 6 pp. 545-551, 1965 
2. B. Ramstedt et al. “Analysis of natural and synthetic sphingomyelins using high-performance thin-layer chromatography” Eur J Biochem., vol. 266 pp. 997-1002, 1999 
3. I. Singh et al. “Lignoceric acid is oxidized in the peroxisome: implications for the Zellweger cerebro-hepato-renal syndrome and adrenoleukodystrophy” Proc Natl Acad Sci U S A., vol. 81 pp. 4203-4207, 1984 
4. Y. Qin et al. “Saturated Very-Long-Chain Fatty Acids Promote Cotton Fiber and Arabidopsis Cell Elongation by Activating Ethylene Biosynthesis” The Plant Cell, vol. 19 pp. 3692-3704, 2007

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