Methyl eicosadienoate (all cis-11,14)Methyl eicosadienoate (all cis-11,14)
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Methyl eicosadienoate (all cis-11,14)

Methyl eicosadienoate; C20:2 (cis, cis-11,14) Methyl ester

This product is the methyl ester of a naturally occurring omega-6 fatty acid that is found mainly in small amounts in animal tissues. Eicosadienoic acid (all cis-11,14) is produced by a delta 9 elongase enzyme from linoleic acid and can be converted into dihomo-gamma-linolenic acid, arachidonic acid, sciadonic acid and other polyunsaturated fatty acids.1 Eicosadienoic acid (all cis-11,14) has been found to be able to modulate the metabolism of polyunsaturated fatty acids and alter the responsiveness of macrophages to inflammatory stimulations.2 Along with other mono and polyunsaturated fatty acids eicosadienoic acid (all cis-11,14) can inhibit the binding of leukotriene B4 to pig neutrophil membranes, which may account in part for it’s anti-inflammatory activities.3 The X-ray powder diffraction pattern of the sodium soap of eicosadienoic acid (all cis-11,14) is typical of the crystalline lamellar phase.4
Cat# Size Price Qty Buy
1193 100 mg £80.75

Additional Information

Property Value or Rating
Product Size 100 mg
Manufacturer Matreya, LLC
Empirical Formula C21H38O2
CAS# 205671
Formula Weight 322.5
Solvent none
Source synthetic
Purity 99%
Analytical Methods GC, TLC
Natural Source Synthetic
Solubility chloroform, hexane, ethyl ether
Physical Appearance A neat liquid
Storage -20°C

1. Y-S. Huang et al. “Expression of fungal desaturase genes in cultured mammalian cells” Molecular and Cellular Biochemistry, vol. 219 pp. 7-11, 2001 
2. Y. Huang, W. Huang, C. Li, and L. Chuang “Eicosadienoic acid differentially modulates production of pro-inflammatory modulators in murine macrophages” Molecular and Cellular Biochemistry, DOI: 10.1007/s11010-011-0924-0, 2011 
3. K. Yagaloff et al. “Essential fatty acids are antagonists of the leukotriene B4 receptor” Prostaglandins, Leukotrienes and Essential Fatty Acids, vol. 52 pp. 293-297, 1995 
4. R. Jandacek, and W. Broering “X-ray diffraction study of sodium soaps of monounsaturated and polyunsaturated fatty acids” Lipids, vol. 24 pp. 1008- 1013, 1989

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