Methyl cis-9,10-methyleneoctadecanoateMethyl cis-9,10-methyleneoctadecanoate
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Methyl cis-9,10-methyleneoctadecanoate

Methyl dihydrosterculate

The fatty acid of this cyclopropanoid fatty acid methyl ester is a major constituent of some seed oils and also occurs in some bacterial membranes but is not synthesized or used by humans.1 Dihydrosterculic acid is a major constituent of the phospholipids of many trypanosomatid flagellates including some pathogenic species. 10-thiastearic acid has been found to be a potent inhibitor of dihydrosterculic acid synthesis and has been used as a therapeutic drug against these organisms.2 The enzyme sadenosylmethionine donates a methylene group to oleic acid in the sn-1 position of phosphatidylethanolamine to form dihydrosterculic acid. Dihydrosterculic acid is further desaturated to sterculic acid by cyclopropane desaturase.
Cat# Size Price Qty Buy
1823 25 mg £281.25

Additional Information

Property Value or Rating
Product Size 25 mg
Manufacturer Matreya, LLC
Empirical Formula C20H38O2
CAS# 3971-54-8
Formula Weight 310.5
Solvent none
Source synthetic
Purity 98+%
Analytical Methods TLC, GC, identity confirmed by MS
Natural Source Synthetic
Solubility chloroform, ethanol, methanol, hexane
Physical Appearance A neat liquid
Storage -20°C
References

1. G. Knothe “NMR Characterization of Dihydrosterculic Acid and Its Methyl Ester” Lipids, Vol. 41(4) pp. 393-396, 2006 
2. R. Pascal, Jr, S. Mannarelli, D. Ziering “10-Thiastearic acid inhibits both dihydrosterculic acid biosynthesis and growth of the protozoan Crithidia fasciculate” The Journal of Biological Chemistry, Vol. 261 pp. 12441-12443, 1986

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