Methyl 3-hydroxyhexanoateMethyl 3-hydroxyhexanoate
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Methyl 3-hydroxyhexanoate

3-Hydroxy C6:0 methyl ester

This 3-hydroxyhexanoic acid methyl ester is a high purity standard that is ideal for analysis and biological systems. Polyhydroxyalkenoates, polyesters produced by bacteria fermentation, are used for carbon and energy storage and are of interest in studies regarding their synthesis, properties and mechanisms. Short chain-length polyhydroxyalkenoate monomers such as 3-hydroxyhexanoic acid may have pharmaceutical properties. The biologically natural chiral (R)-3-hydroxyhexcanoic acid is an intermediate in fatty acid biosynthesis. 3-hydroxyhexanoic acid has been found in patients with ketoacidosis.1 3- hydroxy fatty acids are used as biomarkers for fatty acid oxidative disorders of both the long- and short-chain 3-hydroxyacyl- CoA dehydrogenases.2,3
Cat# Size Price Qty Buy
1748 25 mg £178.13

Additional Information

Property Value or Rating
Product Size 25 mg
Manufacturer Matreya, LLC
Empirical Formula C7H14O3
CAS# 21188-58-9
Formula Weight 146.2
Solvent none
Source synthetic
Purity 98+%
Analytical Methods TLC, GC, identity confirmed by MS
Natural Source Synthetic
Solubility chloroform, ethanol, methanol
Physical Appearance A neat liquid
Storage -20°C
References

1. T. Niwa, K. Yamada, T. Ohki, H. Furukawa “3-Hydroxyhexanoic acid: an abnormal metabolite in urine and serum of diabetic ketoacidotic patients” Journal of Chromatography, vol. 337 pp. 1-7, 1985 
2. P. Jones et al. “Improved Stable Isotope Dilution-Gas Chromatography-Mass Spectrometry Method for Serum or Plasma Free 3-Hydroxy-Fatty Acids and Its Utility for the Study of Disorders of Mitochondrial Fatty Acid beta-Oxidation” Clinical Chemistry, vol. 46, pp. 149-155, 2000 
3. P. Jones et al. “Accumulation of free 3-hydroxy fatty acids in the culture media of fibroblasts from patients deficient in long-chain l-3-hydroxyacyl-CoA dehydrogenase: a useful diagnostic aid” Clinical Chemistry, vol. 47(7) pp. 1190-1194, 2001

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