Methyl 22-hydroxydocosanoateMethyl 22-hydroxydocosanoate
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Methyl 22-hydroxydocosanoate

omega-Hydroxy C22:0 methyl ester

Omega-oxidation is a minor fatty acid pathway used for fatty acid metabolism and usually occurs in the smooth endoplasmic reticulum. Docosanoic acid is enzymaticaly converted to the 22-hydroxydocosanoic acid as well as to the docosanoic dicarboxylic acid as part of the omega-oxidation metabolic pathway.1 22-Hydroxydocosanoic acid is the major aliphatic constituent of green cotton fibers but a very minor component of white cotton fibers.2 Stimulation of omega-hydroxylation has been proposed as a method for treating X-linked adrenoleukodystrophy, a disease that is characterized by elevated levels of very long chain fatty acids.3
Cat# Size Price Qty Buy
1819 25 mg £257.81

Additional Information

Property Value or Rating
Product Size 25 mg
Manufacturer Matreya, LLC
Empirical Formula C23H46O3
CAS# 38646-51-4
Formula Weight 370.6
Solvent none
Source synthetic
Purity 98+%
Analytical Methods TLC, GC
Natural Source Synthetic
Melting Point 73-75°C
Solubility chloroform, warm ethanol, ethyl ether
Physical Appearance A neat solid
Storage room temperature
References

1. R. Sanders et al. “Evidence for two enzymatic pathways for omega-oxidation of docosanoic acid in rat liver microsomes” Journal of Lipid Research, Vol. 46(5) pp. 1001-1008, 2005 
2. L. Yatsu, K. Espelie, P. Kolattukudy “Ultrastructural and chemical evidence that the cell wall of green cotton fiber is suberized” Plant Physiology, Vol. 73(2) pp. 521-524, 1983 
3. R. Sanders et al. “Omega-Oxidation of Very Long-Chain Fatty Acids in Human Liver Microsomes: Implications for X-Linked Adrenoleukodystrophy” Journal of Biological Chemistry, Vol. 281 pp. 13180-13187, 2006

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