Methyl 2-hydroxydecanoateMethyl 2-hydroxydecanoate
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Methyl 2-hydroxydecanoate

2-Hydroxy C10:0 methyl ester

This product is a high purity 2-hydroxy fatty acid methyl ester that is ideal as a standard and for biological systems. alpha- Hydroxy fatty acids are abundant in nervous tissues and are components of cerebrosides and sulfatides, which are mostly found in the myelin of nervous tissues. They are common in cosmetics, skin creams, and lotions. 2-hydroxy acids display complex monolayer phase behavior due to the additional hydrogen bonding afforded by the presence of the second hydroxy group and therefore play an important role in the membrane structure.1 alpha-Oxidation of 2-hydroxy fatty acids to CO2 and saturated acids occurs in the peroxisome and is unique from the alpha-oxidation of beta-carbon branched fatty acids such as phytanic acid. Cells from Zellweger syndrome and peroxisome-deficient cells are unable to undergo alpha-oxidation although patients with other peroxisomal disorders such as X-linked adrenoleukodystrophy, Refsum disease, and rhizomelic chondrodysplasia punctata are able to.2
Cat# Size Price Qty Buy
1759 50 mg £145.31

Additional Information

Property Value or Rating
Product Size 50 mg
Manufacturer Matreya, LLC
Empirical Formula C11H22O3
CAS# 71271-24-4
Formula Weight 202.3
Solvent none
Source synthetic
Purity 98+%
Analytical Methods TLC, GC
Natural Source Synthetic
Solubility methanol, chloroform
Physical Appearance A neat solid
Storage -20°C
References

1. C. Lendrum et al. “Nonequilibrium 2-Hydroxyoctadecanoic Acid Monolayers: Effect of Electrolytes” Langmuir, vol. 27 pp. 4430-4438, 2011 
2. R. Sandhir, M. Khan, and I. Singh “Identification of the Pathway of -Oxidation of Cerebronic Acid in Peroxisomes” Lipids, Vol. 35(10) pp. 1127-1133, 2000

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