Ceramides and Dihydroceramides

Ceramides and their saturated analogs dihydroceramides exert numerous biological effects including induction of cell maturation, cell cycle arrest, terminal cell differentiation, cell senescence, cell death, and skin water-barrier function. Ceramides can also produce reactive oxygen species and stimulate phosphorylation of proteins making them important protein regulators. It is apparent from these effects that ceramides exist at the crux of several enzyme reaction cycles and that experiments involving sphingolipid functions call for control of all of the cycles and their branch-off points. Matreya is the major supplier of these ubiquitous lipids, which can be used as standards for the analysis of tissues and identification and quantitation of major sphingolipids.1,2

References:

  1. D. Mitroi et al., "SGPL1 (sphingosine phosphate lyase 1) modulates neuronal autophagy via phosphatidylethanolamine production" Autophagy Vol. 13:5 pp. 885-899, 2017
  2. T. Sadowski et al., "Large-scale human skin lipidomics by quantitative, high-throughput shotgun mass spectrometry" Sci Rep. Vol. 7(7):43761, 1-11, 2017
Showing 1-50 of 70 Products
  1. N-Triacontanoyl-D-erythro-sphingosine (2049)

    £312.80
    Product Size: 1 mg
    N-C30:0-D-erythro-ceramide
  2. N-Tetracosenoyl-D-erythro-sphingosine (1930)

    £142.80
    Product Size: 5 mg
    N-cis 15-C24:1-D-erythro-Ceramide; N-Nervonoyl-D-erythro-sphingosine
  3. N-Tetracosanoyl-phytosphingosine (2036)

    £134.30
    Product Size: 5 mg
    N-C24:0-Phytoceramide; N-Lignoceroyl-phytosphingosine
  4. N-Tetracosanoyl-D-erythro-sphingosine (1916)

    £112.20
    Product Size: 5 mg
    N-C24:0-D-erythro-Ceramide; N-Lignoceroyl-D-erythro-sphingosine
  5. N-Tetracosanoyl-D-erythro-dihydrosphingosine (2093)

    £290.70
    Product Size: 5 mg
    N-C24:0-D-erythro-dihydroceramide; N-Tetracosanoyl-D-erythro-sphinganine; N-Lignoceryl-D-erythro-dihydrosphingosine
  6. N-Pentadecanoyl-D-erythro-sphingosine (2037)

    £124.95
    Product Size: 10 mg
    N-C15:0-D-erythro-Ceramide
  7. N-omega-Hydroxytriacontanoyl-D-erythro-sphingosine (2080)

    £419.90
    Product Size: 5 mg
    N-omega-Hydroxy-C30:0-D-erythro-ceramide
  8. N-Octanoyl-phytosphingosine (1894)

    £186.40
    Product Size: 5 mg
    N-C8:0-Phytoceramide
  9. N-Octanoyl-L-threo-sphingosine (1830)

    £170.00
    Product Size: 1 mg
    N-C8:0-L-threo-Ceramide
  10. N-Octanoyl-D-threo-sphingosine (1810)

    £170.00
    Product Size: 1 mg
    N-C8:0-D-threo-Ceramide
  11. N-Octanoyl-D-erythro-sphingosine (1903)

    £160.05
    Product Size: 10 mg
    N-C8:0-D-erythro-Ceramide
  12. N-Octanoyl-D-erythro-dihydrosphingosine (1854)

    £58.65
    Product Size: 5 mg
    N-C8:0-D-erythro-Dihydroceramide; N-Octanoyl-D-erythro-sphinganine
  13. N-Octadecenoyl-(cis-9)-D-erythro-sphingosine (1939)

    Starting at: £98.60

    N-C18:1-D-erythro-Ceramide; N-Oleoyl-D-erythro-sphingosine
  14. N-Octadecanoyl-phytosphingosine (2034)

    £120.70
    Product Size: 5 mg
    N-C18:0 Phytoceramide; N-Stearoyl-phytosphingosine
  15. N-Octadecanoyl-L-threo-sphingosine (1843)

    £152.15
    Product Size: 1 mg
    N-C18:0-L-threo-Ceramide; N-Stearoyl-L-threo-sphingosine
  16. N-Octadecanoyl-L-erythro-sphingosine (1850)

    £152.15
    Product Size: 1 mg
    N-C18:0-L-erythro-Ceramide; N-Stearoyl-L-erythro-sphingosine
  17. N-Octadecanoyl-D-threo-sphingosine (1855)

    £170.00
    Product Size: 1 mg
    N-C18:0-D-threo-Ceramide; N-Stearoyl-D-threo-sphingosine
  18. N-Octadecanoyl-D-erythro-sphingosine (1832)

    £100.30
    Product Size: 10 mg
    N-C18:0-D-erythro-Ceramide; N-Stearoyl-D-erythro-sphingosine
  19. N-Octadecanoyl-D-erythro-dihydrosphingosine (2041)

    £134.30
    Product Size: 10 mg
    N-C18:0-D-erythro-Dihydroceramide; N-Octadecanoyl-D-erythro-sphinganine; N-Stearoyl-D-erythro-dihydrosphingosine
  20. N-Nonadecanoyl-D-erythro-sphingosine (2039)

    £142.80
    Product Size: 10 mg
    N-C19:0-D-erythro-Ceramide
  21. N-Hexanoyl-phytosphingosine (1895)

    £186.40
    Product Size: 5 mg
    N-C6:0-Phytoceramide
  22. N-Hexanoyl-NBD-phytosphingosine (1628)

    £178.50
    Product Size: 100 ug
    N-C6:0-NBD-Phytoceramide; N-C6:0-NBD-Phytosphingosine
  23. N-Hexanoyl-NBD-L-threo-sphingosine (1857)

    Starting at: £201.45

    N-C6:0-NBD-Ceramide; N-C6:0-NBD-L-threo-Sphingosine
  24. N-Hexanoyl-NBD-L-threo-dihydrosphingosine (1624)

    £178.50
    Product Size: 100 ug
    N-C6:0-NBD-Dihydroceramide; N-C6:0-NBD-L-threo-Dihydrosphingosine
  25. N-Hexanoyl-NBD-D-erythro-sphingosine (1841)

    Starting at: £168.55

    N-C6:0-NBD-Ceramide; N-C6:0-NBD-D-erythro-Sphingosine
  26. N-Hexanoyl-NBD-D-erythro-dihydrospingosine (1626)

    £178.50
    Product Size: 100 ug
    N-C6:0-NBD-Dihydroceramide; N-C6:0-NBD-D-erythro-Dihydrosphingosine
  27. N-Hexanoyl-L-threo-sphingosine (1828)

    £170.00
    Product Size: 1 mg
    N-C6:0-L-threo-Ceramide
  28. N-Hexanoyl-L-erythro-sphingosine (1848)

    £152.15
    Product Size: 1 mg
    N-C6:0-L-erythro-Ceramide
  29. N-Hexanoyl-D-threo-sphingosine (1809)

    £170.00
    Product Size: 1 mg
    N-C6:0-D-threo-Ceramide
  30. N-Hexanoyl-D-erythro-sphingosine (1900)

    £150.70
    Product Size: 10 mg
    N-C6:0-D-erythro-Ceramide
  31. N-Hexanoyl-D-erythro-dihydrosphingosine (1910)

    £80.75
    Product Size: 5 mg
    N-C6:0-D-erythro-Dihydroceramide; N-Hexanoyl-D-erythro-sphinganine
  32. N-Hexanoyl-biotin-phytosphingosine (2211)

    £312.80
    Product Size: 5 mg
    N-Hexanoyl-biotin-phytosphingosine
  33. N-Hexanoyl-biotin-D-erythro-dihydrosphingosine (2212)

    £481.95
    Product Size: 5 mg
    N-Hexanoyl-biotin-D-erythro-dihydrosphingosine
  34. N-Hexadecanoyl-phytosphingosine (2035)

    £130.05
    Product Size: 5 mg
    N-C16:0-Phytoceramide; N-Palmitoyl-phytosphingosine
  35. N-Hexadecanoyl-D-erythro-sphingosine (C16 sphingolipid base) (2077)

    £326.40
    Product Size: 1 mg
    N-Palmitoyl-D-erythro-(C16 sphingolipid base)
  36. N-Hexadecanoyl-D-erythro-sphingosine (1915)

    £120.70
    Product Size: 10 mg
    N-C16:0-D-erythro-Ceramide; N-Palmitoyl-D-erythro-sphingosine
  37. N-Hexadecanoyl-D-erythro-dihydrosphingosine (2078)

    £134.30
    Product Size: 10 mg
    N-C16:0-D-erythro-Dihydroceramide; N-Hexadecanoyl-D-erythro-sphingosine; N-Palmitoyl-D-erythro-dihydrosphingosine
  38. N-Heptadecanoyl-D-erythro-sphingosine (2038)

    £124.95
    Product Size: 10 mg
    N-C17:0-D-erythro-Ceramide
  39. N-Heptadecanoyl-D-erythro-dihydrosphingosine (2083)

    £134.30
    Product Size: 5 mg
    N-C17:0-D-erythro-dihydroceramide; N-Heptadecanoyl-D-erythro-sphinganine
  40. N-Dotriacontanoyl-D-erythro-sphingosine (2048)

    £196.35
    Product Size: 5 mg
    N-C32:0-D-erythro-Ceramide
  41. N-Dodecanoyl-NBD-phytosphingosine (1627)

    £165.75
    Product Size: 100 ug
    N-C12:0-NBD-Phytoceramide; N-C12:0-NBD-Phytosphingosine
  42. N-Dodecanoyl-NBD-L-threo-sphingosine (1620)

    £201.45
    Product Size: 100 ug
    N-C12:0-NBD-Ceramide; N-C12:0-NBD-L-threo-Sphingosine
  43. N-Dodecanoyl-NBD-L-threo-dihydrosphingosine (1623)

    £178.50
    Product Size: 100 ug
    N-C12:0-NBD-Dihydroceramide; N-C12:0-NBD-L-threo-Dihydrosphingosine
  44. N-Dodecanoyl-NBD-D-erythro-sphingosine (1618)

    Starting at: £134.30

    N-C12:0-NBD-Ceramide; N-C12:0-NBD-D-erythro-Sphingosine
  45. N-Dodecanoyl-NBD-D-erythro-dihydrosphingosine (1625)

    £178.50
    Product Size: 100 ug
    N-C12:0-NBD-Dihydroceramide; N-C12:0-NBD-D-erythro-Dihydrosphingosine
  46. N-Dodecanoyl-D-erythro-sphingosine (1936)

    £112.20
    Product Size: 10 mg
    N-C12:0-D-erythro-Ceramide
  47. N-Docosanoyl-phytosphingosine-d3 (2217)

    £245.65
    Product Size: 500 µg
    N-omega-CD3-Docosanoyl-phytosphingosine; N-C22:0-CD3-phytosphingosine
  48. N-Docosanoyl-phytosphingosine (2140)

    £222.70
    Product Size: 1 mg
    N-C22:0-phytoceramide
  49. N-Decanoyl-D-erythro-sphingosine (1333)

    £112.20
    Product Size: 10 mg
    N-C10:0-D-erythro-Ceramide
  50. N-alpha-Hydroxytetracosanoyl-phytosphingingosine (2094)

    £245.65
    Product Size: 1 mg
    N-(R)-alpha-Hydroxy-C24:0-phytoceramide; N-(R)-Cerebronoyl-phytoceramide