(+)-delta-Tocopherol/ml, 1 ml hexane(+)-delta-Tocopherol/ml, 1 ml hexane
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(+)-delta-Tocopherol/ml, 1 ml hexane

8-Methyltocol

delta-Tocopherol is one of the forms of vitamin E and in animal tissues has been found to have much less retention than alpha-tocopherol.1 Due to its having only one methyl group meta to the phenolic hydroxyl group and no ortho-methyl groups, delta-tocopherol has much less antioxidant activity in vivo than alpha-tocopherol which has two ortho-methyl groups and a meta-methyl group. Vitamin E is involved in immune function, cell signaling, regulation of gene expression, and other metabolic processes. Vitamin E also inhibits lipid oxidation by donating its phenolic hydrogen to lipid free radicals.2 Antioxidant activity in vivo is normally alpha>beta>gamma>delta but the antioxidant potency may depend on various chemical and physical situations.3 The ortho-methyl substitution of the chroman head plays a vital role in the antioxidant activity of tocopherols while the phytyl tail is very important for proper positioning in the biomembranes. The antioxidant properties of vitamin E may delay memory loss in Down’s syndrome patients due to their protection from harmful oxidation caused by excess activity of Superoxide dismutase. Vitamin E is only naturally produced in plants, algae, and some cyanobacteria and is therefore an important dietary nutrient for humans and animals.
Cat# Size Price Qty Buy
1790 50 mg/ml, 1ml £178.13

Additional Information

Property Value or Rating
Product Size 50 mg/ml, 1ml
Manufacturer Matreya, LLC
Empirical Formula C27H46O2
CAS# 119-13-1
Formula Weight 402.7
Solvent hexane
Source natural
Purity TLC, 95%; GC, 98%
Analytical Methods TLC,GC, identity confirmed by MS
Natural Source Plant
Solubility methanol, ethanol, hexane, chloroform
Physical Appearance A 50 mg/ml liquid in hexane
Storage -20°C
References

1. S. Chiku, K. Hamamura and T. Nakamura “Novel urinary metabolite of d-delta-tocopherol in rats” Journal of Lipid Research, Vol. 25 pp. 40-48, 1984 
2. G. W. Burton and K. Ingold Autoxidation of biological molecules. 1. Antioxidant activity of vitamin E and related chain-breaking phenolic antioxidants in vitro, U. J. Am. Chem. Soc., 103, 6472-6477, 1981 
3. Anchalee Sirikhachornkit, Jai W. Shin, Irene Baroli, and Krishna K. Niyogi Replacement of a -tocopherol by ß -tocopherol enhances resistance to photo-oxidative stress in a xanthophyll-deficient strain of Chlamydomonas reinhardtii, Eukaryotic Cell, doi:10.1128, 2009

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