Chloramphenicol research grade, Ph. Eur. (16785-GRP)

Blocks bacterial protein synthesis by inhibiting the peptidyl transferase activity of the 50S ribosomal subunit. Determination in serum by HPLC (1,2), in meat (3). Molecular basis for chloramphenicol resistance (5,6), effects on plants (7). Used for the selection of clones (8).