Aurovist - 1.9 nmAurovist - 1.9 nm
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Aurovist - 1.9 nm

1.9 nm gold nanoparticles containing 40 mg gold metal. Ready to be reconstituted in water, PBS, or other buffer.

AuroVist™ is a novel nanotechnology agent, the first of its kind, which enables greatly enhanced x-ray imaging of blood vessels, the kidneys, tumors, and other organs. It consists of 1.9 nm gold nanoparticles (gold core diameter) with a highly water soluble organic shell making the particles both useable at high concentrations (up to 1.5 g Au/cc) and well tolerated by animals even at high concentrations (LD50 > 1.4 g Au/kg). Some of the significant unique features and advantages of AuroVist™ are listed below:

  • Longer blood residence time than iodine agents (1.9 nm gold core, ~50,000 Da.).
  • High Contrast (> 500 HU initial blood contrast, kidneys >1500 HU).
  • Clears through Kidneys. • Low toxicity (LD50 > 1.4 g Au/kg).
  • Can be concentrated >4 times that of standard iodine agents (up to 1.5 g Au/cc).
  • Permeates angiogenic endothelium of tumors.
  • Up to 10 times the contrast of standard iodine agents (Gold absorbs ~3 times more than an equal weight of iodine at 20 and 100 keV and can be ~4 times more concentrated).
  • Low osmolality, even at high concentrations.
  • Low viscosity, similar to water; easy to inject, even into small vessels.
  • Can image using standard MicroCT, clinical CT, planar X-ray, or mammography.
  • Enhances radiotherapy dose.

It is particularly useful for MicroCT animal imaging; for example, studies of kidneys, tumors, stroke, atherosclerosis and other vascular conditions.

*not approved for human use.

Cat# Size Price Qty Buy
1102-40MGAU 40 mg Au
£465.60
1102A-5X40MGAU 5 x 40 mg Au
£2,078.40

Additional Information

Property Value or Rating
Manufacturer Cat# 1102
Manufacturer Nanoprobes, Inc.

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