Anti-ganglioside GD2, (polyclonal antibody to GD2, isotype IgG, IgM)Anti-ganglioside GD2, (polyclonal antibody to GD2, isotype IgG, IgM)
Move your mouse over image or click to enlarge

Anti-ganglioside GD2, (polyclonal antibody to GD2, isotype IgG, IgM)

Anti-ganglioside GD2 (polyclonal antibody)

Anti-ganglioside GD2 (anti-GD2) is very useful in the identification of disialoganglioside GD2 and in immunotargeting cells expressing disialoganglioside GD2. Several gangliosides have been found to have elevated expressions in tumor cells. Many therapeutic treatments of tumor cells are being investigated using antibodies to target cells that express these elevated levels of gangliosides. Disialoganglioside GD2 has been identified as a tumor-associated antigen and therapeutic approaches using anti-GD2 are being investigated and show great potential.1 Although many challenges must still be overcome in using this therapeutic approach progress is steadily going forward.2
Cat# Size Price Qty Buy
1963 50 ul £348.50

Additional Information

Property Value or Rating
Product Size 50 ul
Manufacturer Matreya, LLC
Formula Weight 0
Solvent none
Source rabbit
Analytical Methods ELISA, TLC immunoblotting
Solubility water
Physical Appearance Purified anti-ganglioside GD22
Storage -20°C
References

1. M. Ozkaynak et al. “Phase I Study of Chimeric Human/Murine Anti–Ganglioside GD2 Monoclonal Antibody (ch14.18) With Granulocyte-Macrophage Colony-Stimulating Factor in Children With Neuroblastoma Immediately After Hematopoietic Stem-Cell Transplantation: A Children’s Cancer Group Study” Journal of Clinical Oncology, Vol 18(24) pp. 4077-4085, 2000 
2. J. Hu et al. “Reducing Epitope Spread during Affinity Maturation of an Anti-Ganglioside GD2 Antibody” The Journal of Immunology, Vol. 186(4) pp. 1-8, 2009

Related Documents