anti- 14-3-3 antibody

anti- 14-3-3 antibody

14-3-3 theta(also known as YWHAQ, or 14-3-3 tau) is a member of 14-3-3 proteins which were the first phosphoserine/phosphothreonine-binding proteins to be discovered. 14-3-3 family members interact with a wide spectrum of proteins and possess diverse functions. Mammals express seven distinct 14-3-3 isoforms(gamma, epsilon, beta, zeta, sigma, theta, tau) that form multiple homo-and hetero-dimmers. 14-3-3 proteins display the highest expression levels in the brain, and have been implicated in several neurodegenerative diseases, including Alzheimer's disease and amyotrophic lateral sclerosis. This antibody was raised against full-length 14-3-3 theta.
Cat# Size Price Qty Buy
FNab00002 100µg £245.00

Additional Information

Property Value or Rating
Product Size 100µg
Manufacturer FineTest
Antibody Type monoclonal
Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Physical Appearance liquid
Purification Protein A+G purification
Purity ≥95% as determined by SDS-PAGE
Host Mouse
Isotype IgG1
Immunogen tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
Alternate Names 14 3 3, 14 3 3 protein T cell, 14 3 3 protein tau, 14 3 3 protein theta, 1C5, HS1, Protein HS1, YWHAQ
Calculated MW 28 kDa
Protein ID P27348
Clone 8D2
Reactivity Human, Mouse, Rat
Applications ELISA, IF, IHC, WB
Recommended dilution WB: 1:1000-1:10000; IHC: 1:20-1:200; IF: 1:20-1:200
Gene ID 10971

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