9(Z),11(Z)-Octadecadienoic acid9(Z),11(Z)-Octadecadienoic acid
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9(Z),11(Z)-Octadecadienoic acid

9-cis, 11-cis-CLA

9(Z),11(Z)-Octadecadienoic acid is a conjugated linoleic acid (CLA), an isomer of linoleic acid. CLA is found mostly in lipids originating in ruminant animals including dairy products. It has several biological properties including anticarcinogenic activity, suppressing in vitro growth of human melanoma, colorectal, and breast cancer cells, and exhibiting anti-atherogenic activity.1 It is thought that CLA itself may not have anti-oxidant capabilities but may produce substances which protect cells from the detrimental effects of peroxides. Due to its being a minor component it is very helpful as a comparison to the major isomers 9(Z),11(E)-CLA and 10(E),12(Z)-CLA. 9(Z),11(Z)-CLA has been demonstrated to have a more potent antiproliferative effect than the more common 9(Z),11(E)-CLA isomer when incubated with human colon cancer cells.
Cat# Size Price Qty Buy
1248 25 mg £145.31

Additional Information

Property Value or Rating
Product Size 25 mg
Manufacturer Matreya, LLC
Empirical Formula C18H32O2
CAS# 544-40-7
Formula Weight 280
Source synthetic
Purity 96+%
Analytical Methods GC; TLC; identity confirmed by MS
Melting Point 40-42°C
Solubility ethanol, methanol, chloroform, ethyl ether
Physical Appearance solid
Storage -20°C
Dry Ice No
Hazardous No
References

1. Helen B. MacDonald, Journal of the American College of Nutrition, Vol. 19, No. 90002, 111S-118S, 2000
2. Mairéad Coakley, Mark C. Johnson, Emma McGrath, Shafiqur Rahman, R. Paul Ross, Gerald F. Fitzgerald, Rosaleen Devery, Catherine Stanton, Nutrition and Cancer, 56(1) pp. 95-102, 2006

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