9(Z),11(E)-Octadecadienoic acid9(Z),11(E)-Octadecadienoic acid
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9(Z),11(E)-Octadecadienoic acid

9-cis, 11-trans CLA

9(Z),11(E)-Octadecadienoic acid is a conjugated linoleic acid (CLA), an isomer of linoleic acid. CLA is found mostly in lipids originating in ruminant animals including dairy products. It has several biological properties including anticarcinogenic activity, suppressing in vitro growth of human melanoma, colorectal, and breast cancer cells, and exhibiting anti-atherogenic activity.1 It is thought that CLA itself may not have anti-oxidant capabilities but may produce substances which protect cells from the detrimental effects of peroxides. 9(Z),11(E)-Octadecadienoic acid is the major natural isomer of CLA constituting 73% to 93% of the total CLA in dairy products2 and it appears to be the most biologically active isomer. It appears to enhance animal growth and inhibit osteoclast formation and activity from human cells,3 as well as decrease LDL:HDL and total HDL:cholesterol levels in humans.4
Cat# Size Price Qty Buy
1245 25 mg £138.55

Additional Information

Property Value or Rating
Product Size 25 mg
Manufacturer Matreya, LLC
Empirical Formula C18H32O2
CAS# 2540-56-9
Formula Weight 280.4
Solvent none
Source synthetic
Purity 98+%
Analytical Methods GC; TLC; identity confirmed by MS
Natural Source Synthetic
Solubility chloroform, ethanol, hexane, methanol, DMSO
Physical Appearance A neat liquid
Storage -20°C

1. Helen B. MacDonald, Journal of the Amer. College of Nutr., Vol 19, No. 90002, 111S-118S, 2000 
2. M. Belury, Annual Review of Nutrition, July Vol.22, 505, 2002 
3. Ilana Platt, Ahmed El-Sohemy, Lipids in Health and Disease, 8:15, 2009 
4. S. Tricon, et al., The American Journal of Clinical Nutrition, 80:614, 2004

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