3-Hydroxyoctadecanoic acid3-Hydroxyoctadecanoic acid
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3-Hydroxyoctadecanoic acid

3-Hydroxy C18:0 fatty acid

This 3-hydroxyoctadecanoic acid is a high purity standard that is ideal for analysis and biological systems. 3- Hydroxyoctadecanoic acid is found in many plants and animals as well as in bacteria and other organisms. 3-Hydroxy fatty acids are intermediates in fatty acid biosynthesis and have been found to be converted to the -fatty acid by the enzyme CYP4F11 and then into dicarboxylic acids in vivo.1 3-Hydroxy fatty acids are used as biomarkers for fatty acid oxidative disorders of both the long- and short-chain 3-hydroxy-acyl-CoA dehydrogenases.2,3 Polyhydroxyalkenoates, polyesters produced by bacteria fermentation, are used for carbon and energy storage and are of interest in studies regarding their synthesis, properties and mechanisms. Medium chain-length polyhydroxyalkenoate monomers such as 3- hydroxyoctadecanoic acid may have pharmaceutical properties.
Cat# Size Price Qty Buy
1743 25 mg £140.63

Additional Information

Property Value or Rating
Product Size 25 mg
Manufacturer Matreya, LLC
Empirical Formula C18H36O3
CAS# 45261-96-9
Formula Weight 300.5
Solvent none
Source synthetic
Purity 98+%
Analytical Methods TLC, GC, identity confirmed by MS
Natural Source Synthetic
Melting Point 52-54°C
Solubility ethanol, methanol
Physical Appearance A neat solid
Storage -20°C
References

1. M. Dhar et al. “Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11” Journal of Lipid Research, vol. 49, pp. 612-624, 2008 
2. P. Jones et al. “Improved Stable Isotope Dilution-Gas Chromatography-Mass Spectrometry Method for Serum or Plasma Free 3-Hydroxy-Fatty Acids and Its Utility for the Study of Disorders of Mitochondrial Fatty Acid ß-Oxidation” Clinical Chemistry, vol. 46, pp. 149-155, 2000 
3. P. Jones et al. “Accumulation of free 3-hydroxy fatty acids in the culture media of fibroblasts from patients deficient in long-chain l-3-hydroxyacyl-CoA dehydrogenase: a useful diagnostic aid” Clinical Chemistry, vol. 47(7) pp. 1190-1194, 2001

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