3-Hydroxyheptadecanoic acid3-Hydroxyheptadecanoic acid
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3-Hydroxyheptadecanoic acid

3-Hydroxy C17:0 fatty acid

3-Hydroxyheptadecanoic acid is a high purity standard that is ideal as a standard or for biological systems. This odd numbered fatty acid is unusual in many biological systems and can therefore be used as a biomarker. 3- Hydroxyheptadecanoic acid has been used to characterize certain bacteria such as some gliding bacteria.1 3-Hydroxy fatty acids have been found to be converted to the omega-fatty acid by the enzyme CYP4F11 and then into dicarboxylic acids in vivo.2 3-hydroxy fatty acids are used as biomarkers for fatty acid oxidative disorders of both the long- and short-chain 3- hydroxy-acyl-CoA dehydrogenases.3,4
Cat# Size Price Qty Buy
1741 25 mg £168.75

Additional Information

Property Value or Rating
Product Size 25 mg
Manufacturer Matreya, LLC
Empirical Formula C17H34O3
CAS# 40165-89-7
Formula Weight 286.5
Solvent none
Source synthetic
Purity 98+%
Analytical Methods TLC, GC
Natural Source Synthetic
Melting Point 93-95°C
Solubility ethanol, methanol
Physical Appearance A neat solid
Storage -20°C
References

1. P. Srisukchayakul et al. “Rapidithrix thailandica gen. nov., sp. nov., a marine gliding bacterium isolated from samples collected from the Andaman sea, along the southern coastline of Thailand” IJSEM, vol. 57 pp. 2275-2279, 2007 
2. M. Dhar et al. “Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11” Journal of Lipid Research, vol. 49, pp. 612-624, 2008 
3. P. Jones et al. “Improved Stable Isotope Dilution-Gas Chromatography-Mass Spectrometry Method for Serum or Plasma Free 3-Hydroxy-Fatty Acids and Its Utility for the Study of Disorders of Mitochondrial Fatty Acid ß-Oxidation” Clinical Chemistry, vol. 46, pp. 149-155, 2000 
4. P. Jones et al. “Accumulation of free 3-hydroxy fatty acids in the culture media of fibroblasts from patients deficient in long-chain l-3-hydroxyacyl-CoA dehydrogenase: a useful diagnostic aid” Clinical Chemistry, vol. 47(7) pp. 1190-1194, 2001

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