3-Hydroxydodecanoic acid3-Hydroxydodecanoic acid
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3-Hydroxydodecanoic acid

3-Hydroxy C12:0 fatty acid

This 3-hydroxydodecanoic acid is a high purity standard that is useful for the investigation of disorders and diseases. Polyhydroxyalkenoates, polyesters produced by bacteria fermentation, are used for carbon and energy storage and are of interest in studies regarding their synthesis, properties and mechanisms. Medium chain-length polyhydroxyalkenoate monomers such as 3-hydroxydodecanoic acid may have pharmaceutical properties. The biologically natural chiral (R)-3- hydroxydodecanoic acid is an intermediate in fatty acid biosynthesis. 3-Hydroxydodecanoic acid is the major fatty acid in some lipopolysaccharides.1 3-hydroxy fatty acids are used as biomarkers for fatty acid oxidative disorders of both the longand short-chain 3-hydroxy-acyl-CoA dehydrogenases.2,3
Cat# Size Price Qty Buy
1731 25 mg £178.13

Additional Information

Property Value or Rating
Product Size 25 mg
Manufacturer Matreya, LLC
Empirical Formula C12H24O3
CAS# 1883-13-2
Formula Weight 216.3
Solvent none
Source synthetic
Purity 98+%
Analytical Methods TLC, GC
Natural Source Synthetic
Melting Point 71-72°C
Solubility methanol, ethanol
Physical Appearance A neat solid
Storage -20°C
References

1. K. Kunii et al. “A new extraction method for Acinetobacter species ODB-L2 rough form lipopolysaccharide from culture broth” Microbios., vol. 105:412 pp. 153-61, 2001 
2. P. Jones et al. “Improved Stable Isotope Dilution-Gas Chromatography-Mass Spectrometry Method for Serum or Plasma Free 3-Hydroxy-Fatty Acids and Its Utility for the Study of Disorders of Mitochondrial Fatty Acid beta-Oxidation” Clinical Chemistry, vol. 46, pp. 149-155, 2000 
3. P. Jones et al. “Accumulation of free 3-hydroxy fatty acids in the culture media of fibroblasts from patients deficient in long-chain l-3- hydroxyacyl-CoA dehydrogenase: a useful diagnostic aid” Clinical Chemistry, vol. 47(7) pp. 1190-1194, 2001

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