3-Hydroxydecanoic acid3-Hydroxydecanoic acid
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3-Hydroxydecanoic acid

3-Hydroxy C10:0 fatty acid

This 3-hydroxydecanoic acid is a high purity standard that is useful for the investigation of disorders and diseases. Polyhydroxyalkenoates, polyesters produced by bacteria fermentation, such as from Escherichia coli, are used for carbon and energy storage and are of interest in studies regarding their synthesis, properties and mechanisms.1 Short chain-length polyhydroxyalkenoate monomers such as 3-hydroxydecanoic acid may have pharmaceutical properties. 3-Hydroxydecanoic acid is the prevalent fatty acid in the rhamnolipid of Pseudomonas aeruginosa.2 The biologically natural chiral (R)-3- hydroxydecanoic acid is an intermediate in fatty acid biosynthesis. 3-hydroxy fatty acids are used as biomarkers for fatty acid oxidative disorders of both the long- and short-chain 3-hydroxy-acyl-CoA dehydrogenases.3,4
Cat# Size Price Qty Buy
1727 25 mg £206.25

Additional Information

Property Value or Rating
Product Size 25 mg
Manufacturer Matreya, LLC
Empirical Formula C10H20O3
CAS# 5561-87-5
Formula Weight 188.3
Solvent none
Source synthetic
Purity 98+%
Analytical Methods TLC, GC, identity confirmed by MS
Natural Source Synthetic
Melting Point 57-60°C
Solubility ethanol, methanol, chloroform
Physical Appearance A neat solid
Storage -20°C
References

1. Z. Zheng et al. “Production of 3-hydroxydecanoic acid by recombinant Escherichia coli HB101 harboring phaG gene” Antonie Van Leeuwenhoek, vol. 85 pp. 93-101, 2004 
2. Q. Wang et al. “Engineering Bacteria for Production of Rhamnolipid as an Agent for Enhanced Oil Recovery” Biotechnology and Bioengineering, vol. 98 pp. 842-853, 2007 
3. P. Jones et al. “Improved Stable Isotope Dilution-Gas Chromatography-Mass Spectrometry Method for Serum or Plasma Free 3-Hydroxy-Fatty Acids and Its Utility for the Study of Disorders of Mitochondrial Fatty Acid ß-Oxidation” Clinical Chemistry, vol. 46, pp. 149-155, 2000 
4. P. Jones et al. “Accumulation of free 3-hydroxy fatty acids in the culture media of fibroblasts from patients deficient in long-chain l-3-hydroxyacyl-CoA dehydrogenase: a useful diagnostic aid” Clinical Chemistry, vol. 47(7) pp. 1190-1194, 2001

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