Ceramides and Dihydroceramides

Ceramides and their saturated analogs dihydroceramides exert numerous biological effects including induction of cell maturation, cell cycle arrest, terminal cell differentiation, cell senescence, cell death, and skin water-barrier function. Ceramides can also produce reactive oxygen species and stimulate phosphorylation of proteins making them important protein regulators. It is apparent from these effects that ceramides exist at the crux of several enzyme reaction cycles and that experiments involving sphingolipid functions call for control of all of the cycles and their branch-off points. Matreya is the major supplier of these ubiquitous lipids, which can be used as standards for the analysis of tissues and identification and quantitation of major sphingolipids.1,2

References:

  1. D. Mitroi et al., "SGPL1 (sphingosine phosphate lyase 1) modulates neuronal autophagy via phosphatidylethanolamine production" Autophagy Vol. 13:5 pp. 885-899, 2017
  2. T. Sadowski et al., "Large-scale human skin lipidomics by quantitative, high-throughput shotgun mass spectrometry" Sci Rep. Vol. 7(7):43761, 1-11, 2017
Showing 1-50 of 70 Products
  1. Ceramides (mixture)

    Ceramides (mixture) (1056)

    £130.05
    Product Size: 25 mg
    Ceramides with hydroxy and non-hydroxy acyl groups
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  2. Ceramides, (hydroxy)

    Ceramides, (hydroxy) (1323)

    Starting at: £98.60

    Ceramides, mostly with hydroxy acyl groups
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  3. Ceramides, (non-hydroxy)

    Ceramides, (non-hydroxy) (1322)

    Starting at: £98.60

    Ceramide, with mostly non-hydroxy acyl groups
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  4. N-(30-Linoleoyloxy-triacontanoyl)-phytosphingosine

    N-(30-Linoleoyloxy-triacontanoyl)-phytosphingosine (2135)

    £402.05
    Product Size: 1 mg
    N-(30-Linoleoyloxy-triacontanoyl)-phytosphingosine
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  5. N-(30-Linoleoyloxy-triacontanoyl)-sphingosine

    N-(30-Linoleoyloxy-triacontanoyl)-sphingosine (2084)

    £402.05
    Product Size: 1 mg
    Ceramide (EOS); EOS Ceramide 1
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  6. N-(R)-alpha-Hydroxytetracosanoyl-D-erythro-dihydrosphingosine

    N-(R)-alpha-Hydroxytetracosanoyl-D-erythro-dihydrosphingosine (2098)

    £290.70
    Product Size: 1 mg
    N-(R)-alpha-Hydroxytetracosanoyl-D-erythro-dihydrosphingosine
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  7. N-(R)-alpha-Hydroxytetracosanoyl-D-erythro-sphingosine

    N-(R)-alpha-Hydroxytetracosanoyl-D-erythro-sphingosine (2096)

    £44.20
    Product Size: 1 mg
    N-(R)-alpha-Hydroxy-C24:0-ceramide; N-(R)-Cerebronoyl-ceramide
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  8. N-(R,S)-alpha-Hydroxydodecanoyl-D-erythro-dihydrosphingosine

    N-(R,S)-alpha-Hydroxydodecanoyl-D-erythro-dihydrosphingosine (2043)

    £232.05
    Product Size: 5 mg
    N-(R,S)-alpha-Hydroxy-C12:0-D-erythro-dihydroceramide
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  9. N-(R,S)-alpha-Hydroxyhexadecanoyl-D-erythro-dihydrosphingosine

    N-(R,S)-alpha-Hydroxyhexadecanoyl-D-erythro-dihydrosphingosine (2047)

    £232.05
    Product Size: 5 mg
    N-(R,S)-alpha-Hydroxy-C16:0-D-erythro-dihydroceramide; N-(R,S)-alpha-Hydroxypalmitoyl-D-erythro-dihydrosphingosine
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  10. N-(R,S)-alpha-Hydroxyoctadecanoyl-D-erythro-dihydrosphingosine

    N-(R,S)-alpha-Hydroxyoctadecanoyl-D-erythro-dihydrosphingosine (2045)

    £232.05
    Product Size: 5 mg
    N-(R,S)-alpha-Hydroxy-C18:0-D-erythro-dihydroceramide; N-(R,S)-alpha-Hydroxystearoyl-D-erythro-dihydrosphingosine
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  11. N-(R,S)-alpha-Hydroxyoctadecanoyl-D-erythro-sphingosine

    N-(R,S)-alpha-Hydroxyoctadecanoyl-D-erythro-sphingosine (2044)

    £214.20
    Product Size: 5 mg
    N-(R,S)-alpha-Hydroxy-C18:0-D-erythro-ceramide; N-(R,S)-alpha-Hydroxystearoyl-D-erythro-sphingosine
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  12. N-(S)-alpha-Hydroxytetracosanoyl-D-erythro-dihydrosphingosine

    N-(S)-alpha-Hydroxytetracosanoyl-D-erythro-dihydrosphingosine (2099)

    £290.70
    Product Size: 1 mg
    N-(S)-alpha-Hydroxytetracosanoyl-D-erythro-dihydrosphingosine
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  13. N-(S)-alpha-Hydroxytetracosanoyl-D-erythro-sphingosine

    N-(S)-alpha-Hydroxytetracosanoyl-D-erythro-sphingosine (2097)

    £44.20
    Product Size: 1 mg
    N-(S)-alpha-Hydroxytetracosanoyl-D-erythro-sphingosine
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  14. N-(S)-alpha-Hydroxytetracosanoyl-phytosphingosine

    N-(S)-alpha-Hydroxytetracosanoyl-phytosphingosine (2095)

    £141.95
    Product Size: 1 mg
    N-(S)-alpha-Hydroxy-C24:0-phytoceramide; N-(S)-Cerebronoyl-phytoceramide
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  15. N-Acetyl-D-erythro-dihydrosphingosine

    N-Acetyl-D-erythro-dihydrosphingosine (1834)

    £62.90
    Product Size: 5 mg
    N-C2:0-D-erythro-Dihydroceramide; N-Acetyl-D-erythro-sphinganine
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  16. N-Acetyl-D-erythro-sphingosine

    N-Acetyl-D-erythro-sphingosine (1901)

    £115.00
    Product Size: 10 mg
    N-C2:0-D-erythro-Ceramide
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  17. N-Acetyl-D-erythro-sphingosine (C14 sphingolipid base)

    N-Acetyl-D-erythro-sphingosine (C14 sphingolipid base) (1842)

    £255.00
    Product Size: 5 mg
    N-C2:0-Ceramide of D-erythro-C14-sphingosine
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  18. N-Acetyl-L-erythro-sphingosine

    N-Acetyl-L-erythro-sphingosine (1847)

    £134.30
    Product Size: 1 mg
    N-C2:0-L-erythro-Ceramide
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  19. N-Acetyl-L-threo-sphingosine

    N-Acetyl-L-threo-sphingosine (1829)

    £147.90
    Product Size: 1 mg
    N-C2:0-L-threo-Ceramide
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  20. N-Acetyl-phytosphingosine

    N-Acetyl-phytosphingosine (1897)

    £186.40
    Product Size: 5 mg
    N-C2:0-Phytoceramide
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  21. N-alpha-Hydroxytetracosanoyl-phytosphingingosine

    N-alpha-Hydroxytetracosanoyl-phytosphingingosine (2094)

    £245.65
    Product Size: 1 mg
    N-(R)-alpha-Hydroxy-C24:0-phytoceramide; N-(R)-Cerebronoyl-phytoceramide
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  22. N-Decanoyl-D-erythro-sphingosine

    N-Decanoyl-D-erythro-sphingosine (1333)

    £112.20
    Product Size: 10 mg
    N-C10:0-D-erythro-Ceramide
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  23. N-Docosanoyl-phytosphingosine

    N-Docosanoyl-phytosphingosine (2140)

    £222.70
    Product Size: 1 mg
    N-C22:0-phytoceramide
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  24. N-Docosanoyl-phytosphingosine-d3

    N-Docosanoyl-phytosphingosine-d3 (2217)

    £245.65
    Product Size: 500 µg
    N-omega-CD3-Docosanoyl-phytosphingosine; N-C22:0-CD3-phytosphingosine
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  25. N-Dodecanoyl-D-erythro-sphingosine

    N-Dodecanoyl-D-erythro-sphingosine (1936)

    £112.20
    Product Size: 10 mg
    N-C12:0-D-erythro-Ceramide
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  26. N-Dodecanoyl-NBD-D-erythro-dihydrosphingosine

    N-Dodecanoyl-NBD-D-erythro-dihydrosphingosine (1625)

    £178.50
    Product Size: 100 ug
    N-C12:0-NBD-Dihydroceramide; N-C12:0-NBD-D-erythro-Dihydrosphingosine
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  27. N-Dodecanoyl-NBD-D-erythro-sphingosine

    N-Dodecanoyl-NBD-D-erythro-sphingosine (1618)

    Starting at: £134.30

    N-C12:0-NBD-Ceramide; N-C12:0-NBD-D-erythro-Sphingosine
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  28. N-Dodecanoyl-NBD-L-threo-dihydrosphingosine

    N-Dodecanoyl-NBD-L-threo-dihydrosphingosine (1623)

    £178.50
    Product Size: 100 ug
    N-C12:0-NBD-Dihydroceramide; N-C12:0-NBD-L-threo-Dihydrosphingosine
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  29. N-Dodecanoyl-NBD-L-threo-sphingosine

    N-Dodecanoyl-NBD-L-threo-sphingosine (1620)

    £201.45
    Product Size: 100 ug
    N-C12:0-NBD-Ceramide; N-C12:0-NBD-L-threo-Sphingosine
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  30. N-Dodecanoyl-NBD-phytosphingosine

    N-Dodecanoyl-NBD-phytosphingosine (1627)

    £165.75
    Product Size: 100 ug
    N-C12:0-NBD-Phytoceramide; N-C12:0-NBD-Phytosphingosine
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  31. N-Dotriacontanoyl-D-erythro-sphingosine

    N-Dotriacontanoyl-D-erythro-sphingosine (2048)

    £196.35
    Product Size: 5 mg
    N-C32:0-D-erythro-Ceramide
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  32. N-Heptadecanoyl-D-erythro-dihydrosphingosine

    N-Heptadecanoyl-D-erythro-dihydrosphingosine (2083)

    £134.30
    Product Size: 5 mg
    N-C17:0-D-erythro-dihydroceramide; N-Heptadecanoyl-D-erythro-sphinganine
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  33. N-Heptadecanoyl-D-erythro-sphingosine

    N-Heptadecanoyl-D-erythro-sphingosine (2038)

    £124.95
    Product Size: 10 mg
    N-C17:0-D-erythro-Ceramide
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  34. N-Hexadecanoyl-D-erythro-dihydrosphingosine

    N-Hexadecanoyl-D-erythro-dihydrosphingosine (2078)

    £134.30
    Product Size: 10 mg
    N-C16:0-D-erythro-Dihydroceramide; N-Hexadecanoyl-D-erythro-sphingosine; N-Palmitoyl-D-erythro-dihydrosphingosine
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  35. N-Hexadecanoyl-D-erythro-sphingosine

    N-Hexadecanoyl-D-erythro-sphingosine (1915)

    £120.70
    Product Size: 10 mg
    N-C16:0-D-erythro-Ceramide; N-Palmitoyl-D-erythro-sphingosine
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  36. N-Hexadecanoyl-D-erythro-sphingosine (C16 sphingolipid base)

    N-Hexadecanoyl-D-erythro-sphingosine (C16 sphingolipid base) (2077)

    £326.40
    Product Size: 1 mg
    N-Palmitoyl-D-erythro-(C16 sphingolipid base)
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  37. N-Hexadecanoyl-phytosphingosine

    N-Hexadecanoyl-phytosphingosine (2035)

    £130.05
    Product Size: 5 mg
    N-C16:0-Phytoceramide; N-Palmitoyl-phytosphingosine
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  38. N-Hexanoyl-biotin-D-erythro-dihydrosphingosine

    N-Hexanoyl-biotin-D-erythro-dihydrosphingosine (2212)

    £481.95
    Product Size: 5 mg
    N-Hexanoyl-biotin-D-erythro-dihydrosphingosine
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  39. N-Hexanoyl-biotin-phytosphingosine

    N-Hexanoyl-biotin-phytosphingosine (2211)

    £312.80
    Product Size: 5 mg
    N-Hexanoyl-biotin-phytosphingosine
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  40. N-Hexanoyl-D-erythro-dihydrosphingosine

    N-Hexanoyl-D-erythro-dihydrosphingosine (1910)

    £80.75
    Product Size: 5 mg
    N-C6:0-D-erythro-Dihydroceramide; N-Hexanoyl-D-erythro-sphinganine
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  41. N-Hexanoyl-D-erythro-sphingosine

    N-Hexanoyl-D-erythro-sphingosine (1900)

    £150.70
    Product Size: 10 mg
    N-C6:0-D-erythro-Ceramide
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  42. N-Hexanoyl-D-threo-sphingosine

    N-Hexanoyl-D-threo-sphingosine (1809)

    £170.00
    Product Size: 1 mg
    N-C6:0-D-threo-Ceramide
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  43. N-Hexanoyl-L-erythro-sphingosine

    N-Hexanoyl-L-erythro-sphingosine (1848)

    £152.15
    Product Size: 1 mg
    N-C6:0-L-erythro-Ceramide
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  44. N-Hexanoyl-L-threo-sphingosine

    N-Hexanoyl-L-threo-sphingosine (1828)

    £170.00
    Product Size: 1 mg
    N-C6:0-L-threo-Ceramide
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  45. N-Hexanoyl-NBD-D-erythro-dihydrospingosine

    N-Hexanoyl-NBD-D-erythro-dihydrospingosine (1626)

    £178.50
    Product Size: 100 ug
    N-C6:0-NBD-Dihydroceramide; N-C6:0-NBD-D-erythro-Dihydrosphingosine
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  46. N-Hexanoyl-NBD-D-erythro-sphingosine

    N-Hexanoyl-NBD-D-erythro-sphingosine (1841)

    Starting at: £168.55

    N-C6:0-NBD-Ceramide; N-C6:0-NBD-D-erythro-Sphingosine
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  47. N-Hexanoyl-NBD-L-threo-dihydrosphingosine

    N-Hexanoyl-NBD-L-threo-dihydrosphingosine (1624)

    £178.50
    Product Size: 100 ug
    N-C6:0-NBD-Dihydroceramide; N-C6:0-NBD-L-threo-Dihydrosphingosine
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  48. N-Hexanoyl-NBD-L-threo-sphingosine

    N-Hexanoyl-NBD-L-threo-sphingosine (1857)

    Starting at: £201.45

    N-C6:0-NBD-Ceramide; N-C6:0-NBD-L-threo-Sphingosine
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  49. N-Hexanoyl-NBD-phytosphingosine

    N-Hexanoyl-NBD-phytosphingosine (1628)

    £178.50
    Product Size: 100 ug
    N-C6:0-NBD-Phytoceramide; N-C6:0-NBD-Phytosphingosine
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  50. N-Hexanoyl-phytosphingosine

    N-Hexanoyl-phytosphingosine (1895)

    £186.40
    Product Size: 5 mg
    N-C6:0-Phytoceramide
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